![]() ![]() The literature is scarce concerning the effects of SIBO on critically ill patients. ![]() The two main conditions that favor microbial overgrowth in the small intestine are decreased acid secretion from the stomach and small bowel dyskinesia. SIBO occurs when the homeostatic mechanisms of the small intestine are disturbed. It is defined as an increase in the number and/or disturbance in the type of bacteria in the upper part of the intestinal tract. It is often involved in various disorders, such as diarrhea and malabsorption. Initially, it was considered quite rare, but today there are reports suggesting a SIBO prevalence between 6 to 15% of healthy, asymptomatic people and reaching 80% in patients with irritable bowel syndrome. Small intestine bacterial overgrowth (SIBO) remains to this day a syndrome that is not fully understood. Small Intestinal Bacterial Overgrowth Critical Illness Intensive Care Unitĭiagnostic Test: Modified hydrogen breath test Secondary outcomes include investigation of the effects of SIBO on ventilator associated pneumonia, as well as ICU length of stay and all-cause in-hospital mortality rate in critically ill patients. The primary objective of this study is assessment of the prevalence of SIBO on ICU patients. Specifically, as all participants are intubated and in need of mechanical ventilation, SIBO diagnosis is based on a non-invasive modified technique for sampling exhaled air from the ventilator tubes and performing a standard hydrogen breath test. Small intestinal bacterial overgrowth (SIBO) syndrome, though associated with potentially serious complications, has not been adequately studied to date in critically ill patients hospitalized in intensive care units (ICU).Ī modified method for SIBO diagnosis is employed concerning a standard breath test. Why Should I Register and Submit Results?. ![]()
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